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“This book is a vital step forward in transforming health care as we know it.”

Senator William H. Frist, MD
Transplant surgeon and former Republican Senate Majority Leader

Compassionomics provides the evidence that one simple tool, compassion, can affect not only the outcomes for our patients, but also the financial health of our organizations and the well-being of our providers.”


Donald Berwick, MD
President emeritus, Institute for Healthcare Improvement

“Powerful, well-researched and timely … Compassionomics is a must read, helping us navigate one of the most important challenges facing the health care world.”

Shawn Achor
New York Times bestselling author of Big Potential and The Happiness Advantage

“This isn’t a ‘self-improvement’ book, but we all should read it, because we all will find a path to feeling better.”

Stephen Klasko, MD
President and CEO, Thomas Jefferson University and Jefferson Health

“… now comes evidence that compassion from caregivers isn’t only proper and just – it actually saves patient lives. Between the data and the stories that bring the data to life, this book is eye-opening for those that provide care as well as those that receive care which makes it a great read for everyone.”

Michael Smerconish
SiriusXM, CNN

“This book offers so many ways to think about compassion, for patients and families, for your [health care] team and colleagues, and for yourself … This is the best book I’ve read in years.”

Maureen Bisognano
President emerita and senior fellow, Institute for Healthcare Improvement

“By sharing stories alongside highly readable summaries of decades of scientific research, Trzeciak and Mazzarelli make a compelling case that compassion is vital to our collective health and well-being.”

Beth A. Lown, MD
Chief medical officer, The Schwartz Center for Compassionate Healthcare

Compassionomics is timely, important, and vital. Whether you are a clinician, administrator, or a patient, its message is a call to action for true change in the way we deliver and receive health care.”

Arthur Caplan, PhD
Mitty professor of bioethics, New York University School of Medicine

“A wonderful, evidence-based book that is a must-read for the health professions.”


Richard Levin, MD
President and CEO, The Arnold P. Gold Foundation

“We finally have a book on this fascinating topic that will empower patients to choose health care providers with a heart. Thank you, Drs. Trzeciak and Mazzarelli, for helping shape medicine’s future for the better!”

Emma Seppälä, PhD
Science Director, Stanford University Center for Compassion and Altruism Research and Education, and author of The Happiness Track

“Health care must evolve from treating diseases to caring for people and their families. This is much more than a semantic difference. In the Health Transformation Alliance, our experience with more than 4 million people clearly validates what Dr. Mazzarelli and Dr. Trzeciak so eloquently argue — compassion and empathy are essential to better health care. Caregivers who practice these principles encourage people to take ownership of their health care — a result that fosters better health outcomes. I hope this book catalyzes a compassionate revolution in our health care system.”

Robert E. Andrews
CEO of the Health Transformation Alliance

“In the dawning of the compassion-centric paradigm of medicine with the new cutting-edge science of compassion, we have been in need of someone to evaluate the hundreds of studies we already have that demonstrate how compassion in medicine positively affects medical outcomes, patient experience, business profitability, and even the well-being of clinicians themselves. Trzeciak and Mazzarelli have done a thorough systematic review of all the studies to date that address the hypothesis that ‘compassion matters.’ They have given us the gift of a very insightful and concise summary of this work and related it to what we do practically every day. Clinicians will feel a validation of their call and their intuition that compassion really does matter. Compassionomics provides the scientific evidence that anyone who practices medicine without compassion is scientifically outdated and committing malpractice.”

Dominic O. Vachon, MDiv, PhD
Director of the Ruth M. Hillebrand Center for Compassionate Care in Medicine at the University of Notre Dame

“At a time when precision medicine has the potential to make the ‘art of medicine’ obsolete, this book demonstrates that the power of healing lies not just in our genome, but also in our soul. Through their journey and scientific explorations, Trzeciak and Mazzarelli remind professionals and patients alike what is truly important and offer a formula for improving healthcare, one patient at a time.”

David Shulkin, MD
Ninth secretary of the Department of Veterans Affairs

“If you’ve ever been a hospital patient, you know that compassion on the part of the caregivers is perhaps the single most important factor affecting your experience. The medical profession, somehow, has failed to see this. It took Drs. Trzeciak and Mazzarelli to make this incredibly important and long overdue observation on compassion. Let’s hope this book is the basis of a revolution on healthcare.”

Steven Levitt
New York Times bestselling author of Freakonomics

“Drs. Trzeciak and Mazzarelli’s proclamation acknowledging the power of courageous caring, now rooted in quantified science, is so timely and essential in the inevitable transition to a consumer-focused healthcare system. This book is a must-read for healthcare providers — indeed, a blueprint for a high-performance culture.”

Calvin H. Knowlton, BSc Pharm, MDiv, PhD
Chairman, CEO, and founder of Tabula Rasa Healthcare, Inc.

Compassionomics is a very important book for everyone engaged in health care, including physicians and nurses, healthcare administrators, educators, and especially patients and their families. It documents the impressive and growing evidence base that supports the critical role that compassionate care plays in shaping outcomes in clinical practice. From ancient times, scholars have described both the ‘art’ and the ‘science’ of the practice of medicine. Compassionomics presents a wonderful distillation of the science behind the art of a healing and health-promoting doctor-patient relationship.”

Robert N. Golden, MD
Dean of the School of Medicine and Public Health and vice chancellor for medical affairs at the University of Wisconsin-Madison

“This well-researched book on such an important topic will be welcome news to all those who strive daily in the front lines of health care provision. They know well the importance of compassion and its effect on outcomes and overall wellbeing — not just for patients but for the providers themselves. With it we win, without it we struggle. This is also a directive to leaders to include compassion as a key criteria in recruitment and promotion. My congratulations to the authors for bringing it center stage.”

Michael J. Dowling
President and CEO of Northwell Health

“Hope is central to progress in health care. And hope is a byproduct of compassion. In Compassionomics, Drs. Trzeciak and Mazzarelli provide not only compelling evidence of how simple acts of compassion positively affect patient outcomes, but they also demonstrate that compassionate care improves the experience of those who work in healthcare. Instilling compassion throughout the delivery of health care will enable the healthcare industry to advance into the future.”

David L. Cohen
Businessman, attorney, and chairman of the board of trustees of the University of Pennsylvania

“The foundation for providing sustainable, quality care is simple: compassion. If we want to keep healthy people out of hospitals, support the most vulnerable of patients or those with long-term issues, and lower healthcare costs, compassion must be at the heart of all these interactions. Drs. Trzeciak and Mazzarrelli’s deep dive into the data that support this fact is second to none. In Compassionomics, they have built the thorough and inspiring case for anyone who wasn’t already convinced that compassion was essential to healthcare and empowered those who are firm believers.”

Jeffrey Brenner, MD
Senior vice president of integrated health and human services at UnitedHealthcare Community & State and MacArthur Fellow

“Today, in these challenging times, we often bear the burden of the pace of change and complexity of care. This book offers so many ways to think about compassion: for patients and families, for your team and colleagues, and for yourself. I can’t think of a more important path than compassion to get to the Institute for Healthcare Improvement’s Triple Aim — better health, better and safer care, and lower costs. This is the best book I’ve read in years.”

Maureen Bisognano
President emerita and senior fellow of the Institute for Healthcare Improvement

“It is easy for hospitals — and thereby physicians — to believe that focusing on volume, rather than quality, will drive results. No one, however, comes into healthcare with this idea in mind; it is a byproduct of an age where systems are stretched thin on time, talent, and resources. Physicians want — and need — to practice in environments that emphasize focus on outcomes and experience. They want — and need — to know that their work makes a difference. With meticulous research, Compassionomics blends these ideas — that physicians can feel proud about their work and produce high-quality outcomes for patients. By focusing on compassionate care, Drs. Trzeciak and Mazzarelli provide a simple, but effective, roadmap toward positively affecting both physician burnout and patient engagement. Compassionomics can help restore the hope for everyone in healthcare that they can have a positive, meaningful career that is driven by human connection, not numbers.”

Robert Bessler, MD
Founder, chairman, and CEO of Sound Physicians

“In Compassionomics, Drs. Mazzarelli and Trzeciak conclusively demonstrate that the power of compassion in medicine is undeniable. Well-researched and comprehensive, the book will be a valuable tool for anyone with a desire to reestablish the primacy of compassion in healthcare.”

Rana Awdish, MD, FCCP
Author of In Shock, My Journey from Death to Recovery and the Redemptive Power of Hope